![SPRAVATO® (esketamine) CIII Nasal Spray: The First and Only N-Methyl D-Aspartate (NMDA) Receptor Antagonist Approved in Conjunction With an Oral Antidepressant for the Treatment of Adults With Treatment-Resistant Depression | Psychiatrist.com SPRAVATO® (esketamine) CIII Nasal Spray: The First and Only N-Methyl D-Aspartate (NMDA) Receptor Antagonist Approved in Conjunction With an Oral Antidepressant for the Treatment of Adults With Treatment-Resistant Depression | Psychiatrist.com](https://www.psychiatrist.com/wp-content/uploads/2021/06/JA18039graphic1.gif)
SPRAVATO® (esketamine) CIII Nasal Spray: The First and Only N-Methyl D-Aspartate (NMDA) Receptor Antagonist Approved in Conjunction With an Oral Antidepressant for the Treatment of Adults With Treatment-Resistant Depression | Psychiatrist.com
![SPRAVATO®▽ (Esketamine) Nasal Spray Approved in Europe for Adults with Treatment-Resistant Major Depressive Disorder | Business Wire SPRAVATO®▽ (Esketamine) Nasal Spray Approved in Europe for Adults with Treatment-Resistant Major Depressive Disorder | Business Wire](https://mms.businesswire.com/media/20191219005272/en/764052/5/jsn_logo_prof_vert_color_rgb.jpg)
SPRAVATO®▽ (Esketamine) Nasal Spray Approved in Europe for Adults with Treatment-Resistant Major Depressive Disorder | Business Wire
![These highlights do not include all the information needed to use SPRAVATO® safely and effectively. See full prescribing information for SPRAVATO®. SPRAVATO® (esketamine) nasal spray, CIII Initial U.S. Approval: 1970 (ketamine) These highlights do not include all the information needed to use SPRAVATO® safely and effectively. See full prescribing information for SPRAVATO®. SPRAVATO® (esketamine) nasal spray, CIII Initial U.S. Approval: 1970 (ketamine)](https://dailymed.nlm.nih.gov/dailymed/image.cfm?name=spravato-01.jpg&id=498018)